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Question:
Response:
Given: Blood is filtered in the glomerulus, which results in the production of primary urine.
Task: Bring the terms listed below into the right order so that they reflect the route of the primary urine through the nephron. Starting point is the renal corpuscle.
Fill in the correct number from the above nephron scheme next to each separate text description. If multiple numbers need to be entered for a description, you should enter them combined in the right order with no separations between the numbers.
9 Receives filtrate produced in the glomerulus
16 Actively transports molecules (like drugs, creatinine and H+) directly from the blood into the tubule. Exchanging Na+ (reabsorbtion) for K+
8345 A u-turn in the tubule where the descending limb allows water to leave and the ascending limb extrudes salt (NaCl) that helps the medulla of the kidney to reabsorb water
7 Collect filtrate from several nephrons, reabsorb water and transport waste to the renal pelvis
128 Forms the juxtaglomerular apparatus together with juxtaglomerular cells and extraglomerular mesangial cells (regulation of bloodpressure)
32 Selectively reabsorbs nutrients (like glucose,amino acids and salts) and water back towards the blood using active transport
1 Site of pressure filtration where small molecules leave the blood
10 Carries blood from the renal artery to the glomerulus and into the peritubular capillary network
13 Outer medulla
12 Cortex
15 Renal papilla
14 Inner medulla
Above you see a kidney slide with an immunohistochemical stain ( selective brown/black color). Such a selective stain gives you specific information about particular tissues and strucure types and their location in the kidney. What specific nephron segment is specifically stained in this histological slide? Think what type of tubuli you expect most at this level in the kidney, you can eliminate some possibilities by looking at the tubule profiles... Hint : Do you see the ratio between the tubuli profiles ? Also, think about the different length of the tubuli segments...
Above you see a kidney slide with an immunohistochemical stain (very selective brownish color) . Such a selective stain gives you specific information about particular tissues and strucure types and their location in the kidney. What specific nephron segment is specifically stained in this histological slide? Hint : this specific stain only colored very few structures in this slide. Think what type of tubuli you expect most at this level, you can eliminate some possibilities by looking at the tubule profiles... Don't get fooled if some debris is caused by coloring artefacts...
Check ALL structures that belong to the renal (or Malpighian) corpuscle.
Above you see a kidney slide with an immunohistochemical stain ( selective brown color). Such a selective stain gives you specific information about particular tissues and strucure types and their location in the kidney. What specific nephron segment is specifically stained in this histological slide? Think what type of tubuli you expect most at this level in the kidney, you can eliminate some possibilities by looking at the tubule profiles... Hint : Do you see the ratio between the tubuli profiles ? Also, think about the different length of the tubuli segments...
Above you see a kidney slide with an immunohistochemical stain (selective blackish color). Such a selective stain gives you specific information about particular tissues and strucure types and their location in the kidney. What specific nephron segment is specifically stained in this histological slide? Think what type of tubuli you expect most at this level in the kidney, you can eliminate some possibilities by looking at the tubule profiles... Hint : Do you see the ratio between the tubuli profiles ? Also, think about the different length of the tubuli segments...
Above you see a kidney slide with an immunohistochemical stain (very selective brownish color) . Such a selective stain gives you specific information about particular tissues and strucure types and their location in the kidney. What specific nephron segment is specifically stained in this histological slide? Think what type of tubuli you expect most at this level in the kidney, you can eliminate some possibilities by looking at the tubule profiles...